What is this test for?
The presence of the MTHFR A1298C polymorphism is associated with reduced methylenetetrahydrofolate reductase enzyme activity and elevated homocysteine levels. This association is reported to be stronger particularly in the homozygous form. It should be evaluated together with other risk factors. It is the tissue plasminogen activator inhibitor. Because increased PAI-1 activation inhibits fibrinolysis, increased clotting is seen. The homozygous 4G allele increases the risk of coagulation and platelet aggregation. Individuals carrying this allele have an increased CAD risk compared with homozygous 5G individuals.
Sample information
- Sample type: Whole Blood (EDTA) 2 tubes
- Tube / container: Purple-top tube
- Sample volume: 5 mL
Preparation
Blood (EDTA) - Purple-top, 2 tubes and Medical History & Consent Form
Testing and results
- Run schedule: Weekdays at 09:00
- Turnaround time: 21 days, 18:00
Price and appointment
Add the test to your list to receive a price quote by e-mail, or call +90 850 640 07 30 / message us on WhatsApp (+90 537 301 22 14). You can have the test done at our branches or with our home blood collection service. Results can be viewed online with your Turkish ID number (or passport number for foreign nationals).